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Growth Factors are peptides or medium-length amino acid sequences (EGF consists of 53 amino acids). Biologically speaking, Growth Factors are cellular signal molecules that can stimulate cell growth, proliferation, healing and/or differentiation. To accomplish these and other biological actions, growth factors activate specific cellular receptors. Receptors are proteins that bind to cells and transmit information to induce changes in cellular biochemistry.

Through molecular techniques in our specialized laboratories, it is possible to produce pure recombinant growth factors and peptides. Growth factors are naturally produced in the tissues of the body where they are synthesized, and act on local cells.

Our R&R ADVANCED GF MASK is a real meal for the skin (rich water in oil texture based on gel-trap technology), which delivers rich overnight treatment.


  • XS Hyaluronic acid: has a low molecular weight and acts as a connective tissue organizer and water-holding substance.
  • Sodium Hyaluronate: comes from a biotechnological process that’s safe and free from contaminants and GMOs. This innovative ingredient can penetrate the skin more effectively than high molecular weight hyaluronic acid, improving the skin’s viscoelastic properties.
  • 100% natural scent (Mandarin essential oil).
  • Myristyl lactate is an ester of lactic acid that acts as a skin lubricant.
  • Growth factors: “Bio-Placenta” TM - Growth factors: a synthetically derived GF blend:
    • Oligopeptide-1: A unique peptide known as Epidermal Growth Factor (EGF) that stimulates skin cell growth and strengthens the skin barrier. A member of the elite group of peptides known as growth factors, EGF stimulates cell division, growth, and differentiation in epithelial cells such as skin cells.
    • Oligopeptide-2: a peptide that consists of 70 amino acids and, similar to EGF, it stimulates cell proliferation and wound healing.
    • Polypeptide-1: a cell signalling protein also called Basic Fibroblast Growth Factor. It stimulates cell proliferation and fibroblast cell growth, it also stimulates the synthesis of collagen and other extracellular-matrix components.
    • Polypeptide- 9: is a cell signalling protein also called Vascular Endothelial
    • Growth Factor. its main function is to stimulate the formation of blood vessels. This plays a role in supplying fibroblast cells with nutrients, in the growth and migration of cells and in wound healing.
    • Polypeptide- 11: FGF can stimulate the growth and proliferation of fibroblast cells.
    • Bacillus/ Folic acid ferment f i l t rate extract: Antioxidant. Acetyl glutamine: Brightening


  • Apply the mask at night, after cleansing, i4 Medical Mist, and your serum. Leave on overnight, and use gentle circular motions to massage the product into your skin.
  • Use 2 - 3 times a week, or as often as your skin needs it.


Beneficial for dry or mature skin, or to assist in reducing the appearance of wrinkles. Improves skin hydration, suppleness, and elasticity.


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